In this paper we propose a new method for shape analysis based on the depth-ordering of shapes. We use this depth-ordering to non-parametrically define depth with respect to a normal control population. This allows us to quantify differences with …
Fusion between an endoscopic movie and a CT can aid specifying the tumor target volume for radiotherapy. That requires a deformable pharyngeal surface registration between a 3D endoscope reconstruction and a CT segmentation. In this paper, we propose …
Low-rank image decomposition has the potential to address a broad range of challenges that routinely occur in clinical practice. Its novelty and utility in the context of atlas-based analysis stems from its ability to handle images containing large …
This paper develops a method for splines on diffeomorphisms for image regression. In contrast to previously proposed methods to capture image changes over time, such as geodesic regression, the method can capture more complex spatio-temporal …
We consider geodesic regression with parametric time-warps. This allows, for example, to capture saturation effects as typically observed during brain development or degeneration. While highly-flexible models to analyze time-varying image and shape …
The purpose of this study is to investigate architectural characteristics of cell arrangements in breast cancer histology images. We propose the use of topological data analysis to summarize the geometric information inherent in tumor cell …
The average diffusion propagator (ADP) obtained from diffusion MRI (dMRI) data encapsulates important structural properties of the underlying tissue. Measures derived from the ADP can be potentially used as markers of tissue integrity in …
We seek to compute a diffeomorphic map between a pair of diffusion-weighted images under large deformation. Unlike existing techniques, our method allows any diffusion model to be fitted after registration for subsequent multifaceted analysis. This …
Magnetic resonance (MR) imaging has been demonstrated to be very useful for clinical diagnosis of Alzheimer’s disease (AD). A common approach to using MR images for AD detection is to spatially normalize the images by non-rigid image registration, …
To be able to statistically compare evolutions of image timeseries data requires a method to express these evolutions in a common coordinate system. This requires a mechanism to transport evolutions between coordinate systems: e.g., parallel …