brain

An optimal control approach for the registration of image time-series

This paper discusses an optimal control approach for the registration of image time-series (growth modeling). It combines and augments work on an optimal control formulation to optical flow with theory from large-displacement diffeomorphic image …

Cortical Correspondence with Probabilistic Fiber Connectivity

This paper presents a novel method of optimizing point-based correspondence among populations of human cortical surfaces by combining structural cues with probabilistic connectivity maps. The proposed method establishes a tradeoff between an even …

Multidimensional classification of hippocampal shape features discriminates Alzheimer's disease and mild cognitive impairment from normal aging

We describe a new method to automatically discriminate between patients with Alzheimer's disease (AD) or mild cognitive impairment (MCI) and elderly controls, based on multidimensional classification of hippocampal shape features. This approach uses …

Near-tubular fiber bundle segmentation for diffusion weighted imaging: Segmentation through frame reorientation

This paper proposes a methodology to segment near-tubular fiber bundles from diffusion weighted magnetic resonance images (DW-MRI). Segmentation is simplified by locally reorienting diffusion information based on large-scale fiber bundle geometry. …

Quantitative examination of a novel clustering method using magnetic resonance diffusion tensor tractography

MR diffusion tensor imaging (DTI) can measure and visualize organization of white matter fibre tracts in vivo. DTI is a relatively new imaging technique, and new tools developed for quantifying fibre tracts require evaluation. The purpose of this …

Restoration of DWI Data Using a Rician LMMSE Estimator

This paper introduces and analyzes a linear minimum mean square error (LMMSE) estimator using a Rician noise model and its recursive version (RLMMSE) for the restoration of diffusion weighted images. A method to estimate the noise level based on …

Segmenting images analytically in shape space

This paper presents a novel analytic technique to perform shape-driven segmentation. In our approach, shapes are represented using binary maps, and linear PCA is utilized to provide shape priors for segmentation. Intensity based probability …

Finsler Tractography for White Matter Connectivity Analysis of the Cingulum Bundle

In this paper, we present a novel approach for the segmentation of white matter tracts based on Finsler active contours. This technique provides an optimal measure of connectivity, explicitly segments the connecting fiber bundle, and is equipped with …

Geodesic-Loxodromes for Diffusion Tensor Interpolation and Difference Measurement

In algorithms for processing diffusion tensor images, two common ingredients are interpolating tensors, and measuring the distance between them. We propose a new class of interpolation paths for tensors, termed geodesic-loxodromes, which explicitly …

Global Medical Shape Analysis Using the Laplace-Beltrami Spectrum

This paper proposes to use the Laplace-Beltrami spectrum (LBS) as a global shape descriptor for medical shape analysis, allowing for shape comparisons using minimal shape preprocessing: no registration, mapping, or remeshing is necessary. The …