Localized difference in the cortex is one of the most useful morphometric traits in human and animal brain studies. There are many tools and methods already developed to automatically measure and analyze cortical thickness for the human brain. …
Registration of image-time series has so far been accomplished (i) by concatenating registrations between image pairs, (ii) by solving a joint estimation problem resulting in piecewise geodesic paths between image pairs, (iii) by kernel based local …
. Standard image registration methods do not account for changes in image appearance. Hence, metamorphosis approaches have been developed which jointly estimate a space deformation and a change in image appearance to construct a spatio-temporal …
The analysis of neuroimaging data from pediatric populations presents several challenges. There are normal variations in brain shape from infancy to adulthood and normal developmental changes related to tissue maturation. Measurement of cortical …
Chorea-acanthocytosis (ChAc) is an uncommon autosomal recessive disorder due to mutations of the VPS13A gene, which encodes for the membrane protein chorein. ChAc presents with progressive limb and orobuccal chorea, but there is often a marked …
Frontostriatal circuit mediated cognitive dysfunction has been implicated in frontotemporal lobar degeneration (FTLD) and may differ across subtypes of FTLD. We manually segmented the neostriatum (caudate nucleus and putamen) in FTLD subtypes: …
This paper proposes a new method to compute connectivity information from diffusion weighted images. It is inspired by graph-based approaches to connectivity definition, but formulates the estimation problem in the continuum. In particular, it …
Existing atlas-building methods for di usion-tensor images are not designed for longitudinal data. This paper proposes a novel longitudinal atlas-building framework explicitly accounting for temporal dependencies of longitudinal MRI data. …
BACKGROUND: Previously, we reported abnormal volume and global shape in the caudate nucleus in schizotypal personality disorder (SPD). Here, we use a new shape measure which importantly permits local in addition to global shape analysis, as well as …
This paper addresses large-displacement-diffeomorphic mapping registration from an optimal control perspective. This viewpoint leads to two complementary formulations. One approach requires the explicit computation of coordinate maps, whereas the …