brain

Uncertainty Quantification for LDDMM Using a Low-Rank Hessian Approximation

This paper presents an approach to estimate the uncertainty of registration parameters for the large displacement diffeomorphic metric mapping (LDDMM) registration framework. Assuming a local multivariate Gaussian distribution as an approximation for …

Depth-Based Shape-Analysis

In this paper we propose a new method for shape analysis based on the depth-ordering of shapes. We use this depth-ordering to non-parametrically define depth with respect to a normal control population. This allows us to quantify differences with …

Large deformation diffeomorphic registration of diffusion-weighted imaging data

We seek to compute a diffeomorphic map between a pair of diffusion-weighted images under large deformation. Unlike existing techniques, our method allows any diffusion model to be fitted after registration for subsequent multifaceted analysis. This …

Low-Rank to the Rescue - Atlas-Based Analyses in the Presence of Pathologies

Low-rank image decomposition has the potential to address a broad range of challenges that routinely occur in clinical practice. Its novelty and utility in the context of atlas-based analysis stems from its ability to handle images containing large …

PORTR: Pre-Operative and Post-Recurrence Brain Tumor Registration

We propose a new method for deformable registration of pre-operative and post-recurrence brain MR scans of glioma patients. Performing this type of intra-subject registration is challenging as tumor, resection, recurrence, and edema cause large …

Time-Warped Geodesic Regression

We consider geodesic regression with parametric time-warps. This allows, for example, to capture saturation effects as typically observed during brain development or degeneration. While highly-flexible models to analyze time-varying image and shape …

Cortical correspondence via sulcal curve-constrained spherical registration with application to Macaque studies

In this work, we present a novel cortical correspondence method with application to the macaque brain. The correspondence method is based on sulcal curve constraints on a spherical deformable registration using spherical harmonics to parameterize the …

Diffusion Propagator Estimation Using Radial Basis Functions

The average diffusion propagator (ADP) obtained from diffusion MRI (dMRI) data encapsulates important structural properties of the underlying tissue. Measures derived from the ADP can be potentially used as markers of tissue integrity in …

Group-Wise Cortical Correspondence via Sulcal Curve-Constrained Entropy Minimization

We present a novel cortical correspondence method employing group-wise registration in a spherical parametrization space for the use in local cortical thickness analysis in human and nonhuman primate neuroimaging studies. The proposed method is …

Large Deformation Diffeomorphic Registration of Diffusion-Weighted Images with Explicit Orientation Optimization

We seek to compute a diffeomorphic map between a pair of diffusion-weighted images under large deformation. Unlike existing techniques, our method allows any diffusion model to be fitted after registration for subsequent multifaceted analysis. This …